A mathematical model for the investigation of combined treatment of radiopharmaceutical therapy and PARP inhibitors
Results demonstrate the potential of this computational model as a step toward the development of the digital twin for systematic exploration and optimization of clinical protocols.
Authors
- Susanne Kossatz (ORCID: https://orcid.org/0000-0002-1908-1782)
- Carlos Ferreira
- Yangmeihui Song (ORCID: https://orcid.org/0000-0002-2694-1736)
- Axel Rominger (ORCID: https://orcid.org/0000-0002-1954-736X)
- Gerhard Glatting (ORCID: https://orcid.org/0000-0001-7916-1576)
- Wolfgang Weber (ORCID: https://orcid.org/0000-0002-7854-4345)
- Kuangyu Shi (ORCID: https://orcid.org/0000-0002-8714-3084)
- Jimin Hong (ORCID: https://orcid.org/0000-0002-4499-2094)
- Marc Ryhiner
Institutions
- University of Bern (CH)
- Universität Ulm (DE)
- University Hospital of Bern (CH)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Technical University of Munich (DE)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1007/s00259-025-07144-y
- Citations
- 2
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Novartis Foundation
- University of Bern