Improved FAPI-radiopharmaceutical pharmacokinetics from the perspectives of a dose escalation study
The study highlights the crucial need for precise FAPI-radiotracer dosing, optimizing PET imaging, reducing radiation exposure, and enhancing treatment by accounting for FAP biology and sFAP's influence on pharmacokinetics.
Authors
- Adrianna Bilinska
- Eleni Gourni (ORCID: https://orcid.org/0000-0003-2198-382X)
- Tilman Läppchen (ORCID: https://orcid.org/0000-0002-7746-1572)
- Euy Sung Moon (ORCID: https://orcid.org/0000-0003-0447-1355)
- Marcel Martin (ORCID: https://orcid.org/0009-0007-9817-7996)
- Axel Rominger (ORCID: https://orcid.org/0000-0002-1954-736X)
- Eirinaios Pilatis
- Frank Rösch
- Chandrasekhar Bal (ORCID: https://orcid.org/0000-0001-6219-6609)
- Sanjana Ballal
- Elena Menéndez
Institutions
- Johannes Gutenberg University Mainz (DE)
- University Hospital of Bern (CH)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1007/s00259-025-07141-1
- Citations
- 12
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 12.54