METABOLÓMICA DE POLYLEPIS RACEMOSA Y UTILIZACIÓN DEL EXTRATO ACUOSO DE SU TALLO EN LA SÍSTESIS DE NANOPARTÍCULAS DE PLATA

The green synthesis of silver nanoparticles (AgNPs) by the action of extracts of plant species has a promising future due to its multiple applications. In this work, we prepare AgNPs with an aqueous extract of Polylepis racemosa rhytidomes, a typical South American plant species whose phytochemistry has been little studied. The metabolomic study of this extract by UHPLC-MS allowed us to identify some organic acids, N-acetylglutamic acid, two glycosylated derivatives of ellagic acid (one of them is a new compound) and three glycosylated triterpenes. Aqueous extracts of Polylepis racemosa rhytidome with extraction times of 2, 6, 12 and 30 minutes were used for the synthesis of AgNPs. By SEM it was observed that the size of the AgNPs was approximately 12 nm, obtained with extracts of 2, 6 and 12 minutes. Finally, by comparing the scans by UHPLC-MS before and after the synthesis of AgNPs, and by the characteristics of the metabolites present, it is deduced that the organic acids of the extract stabilized the nanoparticles generated by the reducing groups present. It is concluded that the extract extraction time is an important study variable in the green synthesis of AgNPs with Polylepis racemosa rhytidome.