Integration of Single Cell and Bulk RNA-Sequencing Reveals Key Genes and Immune Cell Infiltration to Construct a Predictive Model and Identify Drug Targets in Endometriosis

Significant transcriptomic changes and altered immune cell infiltration in the proliferative eutopic endometrium potentially contribute to endometriosis pathogenesis. Our predictive model based on the key genes demonstrates high diagnostic accuracy, offering insights for diagnosis and potential treatment strategies.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-02-01
DOI
https://doi.org/10.2147/jir.s497643
Citations
6
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
10.19
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article

Integration of Single Cell and Bulk RNA-Sequencing Reveals Key Genes and Immune Cell Infiltration to Construct a Predictive Model and Identify Drug Targets in Endometriosis

Hanke Zhang, Yuqing Fang, Yanhui Li, Dan Luo
6 citations
Journal of Inflammation Research
Endometriosis Research and Treatment
10.19
article

Integration of Single Cell and Bulk RNA-Sequencing Reveals Key Genes and Immune Cell Infiltration to Construct a Predictive Model and Identify Drug Targets in Endometriosis

Hanke Zhang, Yuqing Fang, Yanhui Li, Dan Luo
article en
6 citations

Abstract

Significant transcriptomic changes and altered immune cell infiltration in the proliferative eutopic endometrium potentially contribute to endometriosis pathogenesis. Our predictive model based on the key genes demonstrates high diagnostic accuracy, offering insights for diagnosis and potential treatment strategies.

Journal of Inflammation ResearchVol. Volume 18
Union Hospital (HK), Huazhong University of Science and Technology (CN)
Zero hunger
Openalex Percentile: Top 2%
Endometriosis Research and Treatment
10.19
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