Integration of Single Cell and Bulk RNA-Sequencing Reveals Key Genes and Immune Cell Infiltration to Construct a Predictive Model and Identify Drug Targets in Endometriosis
Significant transcriptomic changes and altered immune cell infiltration in the proliferative eutopic endometrium potentially contribute to endometriosis pathogenesis. Our predictive model based on the key genes demonstrates high diagnostic accuracy, offering insights for diagnosis and potential treatment strategies.
Authors
- Hanke Zhang
- Yuqing Fang
- Yanhui Li (ORCID: https://orcid.org/0000-0003-2282-7175)
- Dan Luo (ORCID: https://orcid.org/0009-0006-1414-5739)
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s497643
- Citations
- 6
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.19