Molecular Identification of Adhesion Gene Fima in Porphyromonas Gingivalis Isolated From Periodontitis Patients in Misan City

Introduction: Porphyromonas gingivalis is an anaerobic, gram-negative bacterium that promotes oral dysbiosis and alters host defence mechanisms, contributing to the pathogenesis of periodontitis. The goal of the present study was to isolate and identify pathogenic P. gingivalis from gingivitis and periodontitis patients.Method: Fifty swabs were collected from periodontitis patients attending Special Dental Center, Misan City, Iraq. Porphyromonas gingivalis was identified by PCR and its presence was clinically correlated with periodontal disease. The resistance of P. gingivalis was also tested against antibiotics (ciprofloxacin 5 mcg, carbenicillin 25 mcg, cefoxitin 30 mcg, doxycycline 30 mcg, and nalidixic acid 30 mcg).Results: P. gingivalis was found to be associated with periodontal diseases. The strains were resistant to the antibiotics used in this study.Conclusion: P. gingivalis is responsible for causing gingivitis and periodontitis in humans. The higher age groups are more commonly affected by it. Its strains were found to be resistant to the antibioticsused in this study. How to cite this article:Faroq Z F, Ali M A A, Jabar S K. MolecularIdentification of Adhesion Gene Fima inPorphyromonas Gingivalis Isolated FromPeriodontitis Patients in Misan City. J CommunDis. 2024;56(4):70-75. DOI: https://doi.org/10.24321/0019.5138.202472