Population-Adjusted Indirect Treatment Comparisons of Repotrectinib Among Patients with ROS1+ NSCLC

The analysis demonstrated the strong benefits of repotrectinib in PFS, which was robust across different SAs and supported by numerically favorable results for DoR (where available) and ORR. These results, alongside the published TRIDENT-1 clinical data, further support repotrectinib as a potential new standard of care for TKI-naïve patients with <i>ROS1+</i> aNSCLC.

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Publication Details

Journal
Cancers
Published
2025-02-22
DOI
https://doi.org/10.3390/cancers17050748
Citations
1
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
1.52
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article

Population-Adjusted Indirect Treatment Comparisons of Repotrectinib Among Patients with ROS1+ NSCLC

Yong Yuan, Ellen Korol, Madeleine Crabtree, Alexander Edward Dela Cruz Drilon et al.
1 citations
Cancers
Lung Cancer Treatments and Mutations
1.52
article

Population-Adjusted Indirect Treatment Comparisons of Repotrectinib Among Patients with ROS1+ NSCLC

Yong Yuan, Ellen Korol, Madeleine Crabtree, Alexander Edward Dela Cruz Drilon, Byoung Chul Cho, C. Calvet, D. Ross Camidge, Greta Lozano‐Ortega, SARAH G.C. KORPACH, Lavanya Huria, Sarah Goring, Adam Lee, Jürgen Wolf, Dieter Ayers
article en
1 citations

Abstract

The analysis demonstrated the strong benefits of repotrectinib in PFS, which was robust across different SAs and supported by numerically favorable results for DoR (where available) and ORR. These results, alongside the published TRIDENT-1 clinical data, further support repotrectinib as a potential new standard of care for TKI-naïve patients with <i>ROS1+</i> aNSCLC.

CancersVol. 17(5)
Memorial Sloan Kettering Cancer Center (US), Yonsei University (KR), Cornell University (US), Bristol-Myers Squibb (United States) (US), Bristol-Myers Squibb (United Kingdom) (GB), University of Colorado Cancer Center (US), University Hospital Cologne (DE), University of Colorado Denver (US)
Openalex Percentile: Top 22%
Lung Cancer Treatments and Mutations
1.52
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Population-Adjusted Indirect Treatment Comparisons of Repotrectinib Among Patients with ROS1+ NSCLC — Yong Yuan, Ellen Korol, et al. · Cancers (2025) | TGRS Research Map | TGRS