Case report of a seminal vesicle schwannoma involving prostate and bladder: diagnostic pathway and management

Seminal vesicle neoplasms are extremely rare. Schwannoma is a benign tumor of the peripheral nerve sheath composed of Schwann cells. Most of these tumors are silent and become symptomatic with compression of adjacent organs and nerves. We present a case of a 65-year-old man with a history of predominant storage lower urinary tract symptoms. Prostate-specific antigen was within normal ranges, and imaging documented a nodular lesion in the prostate, one in the left seminal vesicle and another one adjacent to the right bladder wall. We successfully performed a prostate biopsy and a trans-urethral resection of the bladder to excise and typify the lesion. Histopathology investigation revealed the final diagnosis of schwannoma.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1093/jscr/rjaf094
Primary Topic
Neurofibromatosis and Schwannoma Cases
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article
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article

Case report of a seminal vesicle schwannoma involving prostate and bladder: diagnostic pathway and management

Giorgio Martino, Damiano Graziani, Onofrio Antonio Rera, Alessandro Zucchi et al.
Journal of Surgical Case Reports
Neurofibromatosis and Schwannoma Cases
article

Case report of a seminal vesicle schwannoma involving prostate and bladder: diagnostic pathway and management

Giorgio Martino, Damiano Graziani, Onofrio Antonio Rera, Alessandro Zucchi, Andrea Fuschi, Manfredi Bruno Sequi, Antonino Carbone, G. De Gregorio, Silvio Scalzo, Antonio Luigi Pastore, Vincenzo Petrozza, Paola Capodiferro, Fabio Maria Valenzi, Alice Antonioni, Giorgio Bozzini, Yazan Al Salhi, Giuseppe Candita, Luca Erra, Kostika Lako, Paolo Pietro Suraci, Filippo Gianfrancesco
article en

Abstract

Seminal vesicle neoplasms are extremely rare. Schwannoma is a benign tumor of the peripheral nerve sheath composed of Schwann cells. Most of these tumors are silent and become symptomatic with compression of adjacent organs and nerves. We present a case of a 65-year-old man with a history of predominant storage lower urinary tract symptoms. Prostate-specific antigen was within normal ranges, and imaging documented a nodular lesion in the prostate, one in the left seminal vesicle and another one adjacent to the right bladder wall. We successfully performed a prostate biopsy and a trans-urethral resection of the bladder to excise and typify the lesion. Histopathology investigation revealed the final diagnosis of schwannoma.

Journal of Surgical Case ReportsVol. 2025(2)
University of Pisa (IT), Ospedale Sant'Anna (IT), Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 94%
Neurofibromatosis and Schwannoma Cases
DOIOpen Access PDFOpenAlex
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Case report of a seminal vesicle schwannoma involving prostate and bladder: diagnostic pathway and management — Giorgio Martino, Damiano Graziani, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS