Neuromuscular Junction Damage in the Calf Muscles of Patients With Advanced Peripheral Artery Disease
Our data demonstrate deterioration of the motor nerve terminals and nAChR clusters, which may compromise neuromuscular transmission, and contribute to the severe leg dysfunction observed in patients with PAD.
Authors
- Julian K. Kim
- Huiyin Tu
- Yuqian Tian (ORCID: https://orcid.org/0000-0002-4279-190X)
- Ali Hakim (ORCID: https://orcid.org/0000-0003-0251-4075)
- Zhen Zhu (ORCID: https://orcid.org/0000-0002-4840-0869)
- Iraklis I. Pipinos (ORCID: https://orcid.org/0000-0001-6873-6346)
- Yu‐Long Li (ORCID: https://orcid.org/0000-0001-5407-2761)
Institutions
- VA Nebraska Western Iowa Health Care System (US)
- University of Nebraska Medical Center (US)
Publication Details
- Journal
- Neuropathology and Applied Neurobiology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/nan.70008
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of General Medical Sciences