[Cytomegalovirus Encephalitis Presenting With Palpitations as the Initial Symptom After Hematopoietic Stem Cell Transplantation to Treat Acute Lymphoblastic Leukemia in a Child: A Case Report].

Hematopoietic stem cell transplantation (HSCT) patients may develop cytomegalovirus encephalitis, a rare but life-threatening complication with a mortality rate exceeding 90%. Cytomegalovirus encephalitis is rare and does not have specific clinical manifestations, which makes clinical diagnosis more difficult. This article reports a pediatric case of acute lymphoblastic leukemia (ALL) with early onset (81 d after transplantation) cytomegalovirus encephalitis after HSCT, with palpitations presenting as the initial symptom. The patient exhibited rapid clinical progression and the treatment was ineffective. This case report can help clinicians gain further understanding of the high-risk factors and clinical features of central nervous system complications following HSCT. When encountering unexplained tachycardia, clinicians should still be vigilant for the possibility of intracranial infection even in the absence of typical neurological manifestations associated with encephalitis. Early recognition and management may help improve the outcomes of such patients.

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Publication Details

Journal
PubMed
Published
2024-11-20
DOI
https://doi.org/10.12182/20241160110
Citations
1
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.39
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article

[Cytomegalovirus Encephalitis Presenting With Palpitations as the Initial Symptom After Hematopoietic Stem Cell Transplantation to Treat Acute Lymphoblastic Leukemia in a Child: A Case Report].

Guoqian He, Yulin Chen, Xiaoping Zhang, Ling Xiao et al.
1 citations
PubMed
Cytomegalovirus and herpesvirus research
0.39
article

[Cytomegalovirus Encephalitis Presenting With Palpitations as the Initial Symptom After Hematopoietic Stem Cell Transplantation to Treat Acute Lymphoblastic Leukemia in a Child: A Case Report].

Guoqian He, Yulin Chen, Xiaoping Zhang, Ling Xiao, Lina Qiao
article en
1 citations

Abstract

Hematopoietic stem cell transplantation (HSCT) patients may develop cytomegalovirus encephalitis, a rare but life-threatening complication with a mortality rate exceeding 90%. Cytomegalovirus encephalitis is rare and does not have specific clinical manifestations, which makes clinical diagnosis more difficult. This article reports a pediatric case of acute lymphoblastic leukemia (ALL) with early onset (81 d after transplantation) cytomegalovirus encephalitis after HSCT, with palpitations presenting as the initial symptom. The patient exhibited rapid clinical progression and the treatment was ineffective. This case report can help clinicians gain further understanding of the high-risk factors and clinical features of central nervous system complications following HSCT. When encountering unexplained tachycardia, clinicians should still be vigilant for the possibility of intracranial infection even in the absence of typical neurological manifestations associated with encephalitis. Early recognition and management may help improve the outcomes of such patients.

PubMedVol. 55(6)
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN)
Openalex Percentile: Top 30%
Cytomegalovirus and herpesvirus research
0.39
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[Cytomegalovirus Encephalitis Presenting With Palpitations as the Initial Symptom After Hematopoietic Stem Cell Transplantation to Treat Acute Lymphoblastic Leukemia in a Child: A Case Report]. — Guoqian He, Yulin Chen, et al. · PubMed (2024) | TGRS Research Map | TGRS