Characterizing the olfaction and dementia association in the community‐based ARIC study
We examined olfactory status and olfactory change in relation to incident dementia. Poor olfactory status was robustly associated with higher dementia rate. Associations were robust across subgroups of age, sex, race, and APOE ε4 status. Persistent poor olfaction or decline over time showed the strongest associations.
Authors
- Honglei Chen (ORCID: https://orcid.org/0000-0003-3446-7779)
- Jennifer A. Deal (ORCID: https://orcid.org/0000-0002-6985-048X)
- Yaqun Yuan (ORCID: https://orcid.org/0000-0002-9825-7474)
- Xiaoqian Zhu (ORCID: https://orcid.org/0009-0007-7357-7985)
- Anna Kucharska‐Newton (ORCID: https://orcid.org/0000-0001-9864-467X)
- Priya Palta
- Thomas H. Mosley (ORCID: https://orcid.org/0000-0003-3343-1352)
- Vidyulata Kamath (ORCID: https://orcid.org/0000-0001-7711-3597)
- Michael Griswold (ORCID: https://orcid.org/0000-0001-8106-5516)
- Srishti Shrestha
Institutions
- University of North Carolina at Chapel Hill (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- University of Mississippi Medical Center (US)
- Michigan State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/alz.14613
- Citations
- 3
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.39
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute on Deafness and Other Communication Disorders
- National Institute of Neurological Disorders and Stroke