Berberine Intervention Mitigates Myocardial Ischemia-Reperfusion Injury in a Rat Model: Mechanistic Insights via miR-184 Signaling
Berberine and miR-184 inhibition offer significant protection against myocardial ischemia-reperfusion injury. These findings suggest that targeting miR-184 and associated pathways may be a promising therapeutic strategy for reducing cardiac damage following ischemia-reperfusion.
Authors
- Gang Cao (ORCID: https://orcid.org/0000-0003-0761-7305)
- Zhikun Zhao
- Yong Wang (ORCID: https://orcid.org/0009-0008-5176-965X)
- Xia Li (ORCID: https://orcid.org/0000-0003-3050-8529)
- Haichen Yang
- Fei Xu
Institutions
- Xuzhou Medical College (CN)
- Huaian First People’s Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Jiangsu Shengze Hospital (CN)
Publication Details
- Journal
- Biologics
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/btt.s479430
- Citations
- 1
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 1.39