Clinical Characteristics Analysis of 30 Cases of Interferon-γ Autoantibody-Positive Patients with Concurrent Mycobacterial Infection: A 6-Year Retrospective Study
Immune deficiency associated with positive anti-IFN-γ autoantibodies resembles the immunosuppression seen in advanced stages of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS), rendering patients highly susceptible to opportunistic infections. These infections were predominantly caused by NTM, followed by MTB and <i>Talaromyces marneffei</i> (TM). This represents a novel immune deficiency syndrome that predisposes patients to a spectrum of opportunistic infections.
Authors
- Yemin Lan (ORCID: https://orcid.org/0000-0003-3455-3618)
- Huawei He (ORCID: https://orcid.org/0000-0002-3805-8940)
- Chunyan Zhao (ORCID: https://orcid.org/0000-0002-4905-0952)
- Lili Luo
- Yan Lin (ORCID: https://orcid.org/0000-0002-7055-3183)
- Xiang‐Guo Meng (ORCID: https://orcid.org/0000-0003-4359-7161)
- Weiwen Li (ORCID: https://orcid.org/0000-0003-3545-6430)
- Shao-Yong Xi
- Chaoyan Xu
- Ai-Chun Huang
- Qingdong Zhu (ORCID: https://orcid.org/0009-0003-3368-5296)
- Chang Song
- Xianzhen Huang
Institutions
- Guangxi Medical University (CN)
- The Fourth People's Hospital (CN)
- The Second Nanning People's Hospital (CN)
- First People's Hospital of Nanning (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/idr.s493956
- Citations
- 2
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 2.71