Single-Cell RNA Sequencing Reveals Peripheral Immune Cell Senescence and Inflammatory Phenotypes in Patients with Premature Ovarian Failure
In summary, this study provides in-depth insights into the immune landscape of POF, revealing distinct cell populations, pathways, and signaling networks linked to the disease. These findings enhance our understanding of POF's immunological mechanisms, contributing to the development of potential diagnostic and therapeutic strategies.
Authors
- Yan Sun (ORCID: https://orcid.org/0000-0003-2595-0961)
- Jing Yan Cai (ORCID: https://orcid.org/0000-0001-6934-0108)
- Jianan Liu (ORCID: https://orcid.org/0009-0004-7420-1136)
- Songjun Li (ORCID: https://orcid.org/0000-0003-3457-7580)
- Weijun Zhong (ORCID: https://orcid.org/0000-0003-3873-3472)
- Jiayi Li (ORCID: https://orcid.org/0000-0003-3515-9073)
- Fu Xiong (ORCID: https://orcid.org/0009-0008-1693-1228)
- Yanhui Liu
- Li Ping Wang (ORCID: https://orcid.org/0000-0001-6893-3809)
Institutions
- Key Laboratory of Guangdong Province (CN)
- Cell Technology (China) (HK)
- Zhujiang Hospital (CN)
- Dongguan People’s Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s496130
- Citations
- 3
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 2.39