Morphological picture of the wound process when using analogues of endogenous peptides in patients with diabetic foot syndrome

The article presents an analysis of the results of outpatient treatment of patients with trophic ulcers against the background of the neuroischemic form of diabetic foot syndrome. The study involved 156 patients divided into 2 comparable groups. The main group (n=78) – together with standard treatment, patients received a synthetic analogue of endogenous regulatory peptides xymedon, 1 tablet 3 times a day from the first day, for 1 month. The comparison group (n=78) received only standard treatment. An analysis of bacterioscopic, cytological and histological studies of trophic ulcers of the foot in both groups was carried out in dynamics. The results of treatment of patients with trophic ulcers of diabetic foot syndrome allow us to conclude that the inclusion of an analogue of endogenous peptides in the complex therapy allows more effectively, compared with the standard method of treatment, to improve the sanitation and regeneration in the foot wound and accelerate the healing time

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Publication Details

Journal
Vrach
Published
2025-02-23
DOI
https://doi.org/10.29296/25877305-2025-02-14
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
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article

Morphological picture of the wound process when using analogues of endogenous peptides in patients with diabetic foot syndrome

P. S. Lukin, С. А. Денисов, Константин Александрович Корейба, Д. Г. Амарантов et al.
Vrach
Wound Healing and Treatments
article

Morphological picture of the wound process when using analogues of endogenous peptides in patients with diabetic foot syndrome

P. S. Lukin, С. А. Денисов, Константин Александрович Корейба, Д. Г. Амарантов, E. B. Elshin, E. Krivoshchekov
article en

Abstract

The article presents an analysis of the results of outpatient treatment of patients with trophic ulcers against the background of the neuroischemic form of diabetic foot syndrome. The study involved 156 patients divided into 2 comparable groups. The main group (n=78) – together with standard treatment, patients received a synthetic analogue of endogenous regulatory peptides xymedon, 1 tablet 3 times a day from the first day, for 1 month. The comparison group (n=78) received only standard treatment. An analysis of bacterioscopic, cytological and histological studies of trophic ulcers of the foot in both groups was carried out in dynamics. The results of treatment of patients with trophic ulcers of diabetic foot syndrome allow us to conclude that the inclusion of an analogue of endogenous peptides in the complex therapy allows more effectively, compared with the standard method of treatment, to improve the sanitation and regeneration in the foot wound and accelerate the healing time

Vrach
Kazan State Medical University (RU), Perm State Medical Academy (RU), Ministry of Health of the Russian Federation (RU), Samara State Medical University (RU), City Clinical Hospital (RU), St. Petersburg State Medical Academy "City Polyclinic №44" (RU)
Openalex Percentile: Top 96%
Wound Healing and Treatments
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Morphological picture of the wound process when using analogues of endogenous peptides in patients with diabetic foot syndrome — P. S. Lukin, С. А. Денисов, et al. · Vrach (2025) | TGRS Research Map | TGRS