Total Astragalus saponins promote ferroptosis in gastric cancer cells by upregulating SIRT3
TAS has therapeutic potential for GC and can effectively inhibit the proliferation and viability of SGC-7901 cells, and the mechanism may be that TAS upregulates SIRT3 to promote the ferroptosis of SGC-7901 cells.
Authors
- Rui Wang (ORCID: https://orcid.org/0000-0003-0773-2127)
- Chengyin Li (ORCID: https://orcid.org/0000-0003-2450-9760)
- Qiyuan Wang (ORCID: https://orcid.org/0000-0003-2529-6226)
- Zhongyi Zhu (ORCID: https://orcid.org/0000-0003-1921-567X)
- Yue Zou
- Jingling Zhao (ORCID: https://orcid.org/0000-0002-7845-9204)
- Xiaocui Jiang
- Min Xiao (ORCID: https://orcid.org/0000-0001-7641-3926)
Institutions
- Hubei University of Chinese Medicine (CN)
- Hubei Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/tcr-24-1421
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56