Comprehensive bioinformatics analysis of co-mutation of FLG2 and TP53 reveals prognostic effect and influences on the immune infiltration in ovarian serous cystadenocarcinoma

In the context of OV, the concurrent mutation of <i>FLG2</i> and <i>TP53</i> not only induces immune activation, but also helps identify a subset of patients with a more favorable prognosis.

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Publication Details

Journal
Translational Cancer Research
Published
2025-02-01
DOI
https://doi.org/10.21037/tcr-24-1596
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive bioinformatics analysis of co-mutation of FLG2 and TP53 reveals prognostic effect and influences on the immune infiltration in ovarian serous cystadenocarcinoma

Jin Hao, Meng Li, Dongmei Han
Translational Cancer Research
Ovarian cancer diagnosis and treatment
article

Comprehensive bioinformatics analysis of co-mutation of FLG2 and TP53 reveals prognostic effect and influences on the immune infiltration in ovarian serous cystadenocarcinoma

Jin Hao, Meng Li, Dongmei Han
article en

Abstract

In the context of OV, the concurrent mutation of <i>FLG2</i> and <i>TP53</i> not only induces immune activation, but also helps identify a subset of patients with a more favorable prognosis.

Translational Cancer ResearchVol. 14(2)
Tianjin Medical University Cancer Institute and Hospital (CN)
Zero hunger
Openalex Percentile: Top 95%
Ovarian cancer diagnosis and treatment
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