Integrative analysis of mitochondrial and immune pathways in diabetic kidney disease: identification of AASS and CASP3 as key predictors and therapeutic targets
Our findings establish AASS and CASP3 as dual biomarkers and therapeutic targets, bridging mitochondrial-immune crosstalk to DKD pathogenesis. This multi-omics framework provides actionable insights for targeting kidney damage in diabetes.
Authors
- Wei Jiang (ORCID: https://orcid.org/0000-0003-1591-4721)
- Yongzheng Hu
- Xin‐Xin Yu (ORCID: https://orcid.org/0000-0002-4477-7589)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Eighth People's Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1080/0886022x.2025.2465811
- Citations
- 4
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 5.72
Funders
- Qingdao Key Health Discipline Development Fund
- National Natural Science Foundation of China