Dose measurement of ophthalmic Ru-106/Rh-106 applicators with a diamond detector calibrated in a clinical megavoltage electron beam

<i>Objective.</i>Uveal melanomas and retinoblastomas can be treated with ophthalmic beta-emitting ruthenium-106/rhodium-106 applicators. The applicator manufacturer provides a datasheet of the dosimetric properties of each applicator set, but the source strengths and 3D dose distributions should be verified by the end user with independent measurements.<i>Approach.</i>The purpose of this work was to calibrate diamond detector against low energy electron beam and determine necessary correction factors in the geometry of ophthalmic applicators to be able to perform quality assurance (QA) measurements for the applicators. Two separate sets of applicators were evaluated.<i>Main results.</i>The results showed good agreement with manufacturers' specifications. An average agreement of 3% to the manufacturer's reference data was observed: measured dose rate/reference = 0.97 ± 0.04 (mean ± SD), range 0.90-1.05.<i>Significance.</i>It can be concluded that megavoltage electron beam is suitable for calibration of a diamond detector. After calibration, detector can be used for an absolute dose measurement of a ruthenium-106/rhodium-106 applicator with sufficient performance to detect deviations larger than 10% in the QA before clinical use.

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Publication Details

Journal
Physics in Medicine and Biology
Published
2025-02-24
DOI
https://doi.org/10.1088/1361-6560/adb9b1
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
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article

Dose measurement of ophthalmic Ru-106/Rh-106 applicators with a diamond detector calibrated in a clinical megavoltage electron beam

Satu Strengell, Assi Valve, Anna Rintala, Katri Nousiainen et al.
Physics in Medicine and Biology
Ocular Oncology and Treatments
article

Dose measurement of ophthalmic Ru-106/Rh-106 applicators with a diamond detector calibrated in a clinical megavoltage electron beam

Satu Strengell, Assi Valve, Anna Rintala, Katri Nousiainen, Vappu Reijonen, Mikko Tenhunen
article en

Abstract

<i>Objective.</i>Uveal melanomas and retinoblastomas can be treated with ophthalmic beta-emitting ruthenium-106/rhodium-106 applicators. The applicator manufacturer provides a datasheet of the dosimetric properties of each applicator set, but the source strengths and 3D dose distributions should be verified by the end user with independent measurements.<i>Approach.</i>The purpose of this work was to calibrate diamond detector against low energy electron beam and determine necessary correction factors in the geometry of ophthalmic applicators to be able to perform quality assurance (QA) measurements for the applicators. Two separate sets of applicators were evaluated.<i>Main results.</i>The results showed good agreement with manufacturers' specifications. An average agreement of 3% to the manufacturer's reference data was observed: measured dose rate/reference = 0.97 ± 0.04 (mean ± SD), range 0.90-1.05.<i>Significance.</i>It can be concluded that megavoltage electron beam is suitable for calibration of a diamond detector. After calibration, detector can be used for an absolute dose measurement of a ruthenium-106/rhodium-106 applicator with sufficient performance to detect deviations larger than 10% in the QA before clinical use.

Physics in Medicine and BiologyVol. 70(6)
University of Helsinki (FI), Helsinki University Hospital (FI)
Affordable and clean energy
Openalex Percentile: Top 94%
Ocular Oncology and Treatments
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