Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson’s disease

Our study provides insights into the shared molecular characteristics of PD and melanoma, identifying potential biomarkers for early diagnosis and prognosis and revealing new therapeutic targets. The discovery of retinoic acid as a promising therapeutic agent represents a significant step forward in drug development and treatment strategies for these diseases. This comprehensive analysis enhances our understanding of the intricate molecular mechanisms underlying the association between PD and melanoma, paving the way for further research and therapeutic advancements. The findings hold the promise of improved diagnosis, prognosis, and personalized treatment strategies for individuals affected by these debilitating diseases.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-02-24
DOI
https://doi.org/10.3389/fgene.2025.1526018
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson’s disease

Zheng Xu, Limei Zhang, Dailin Li, Zhiqiang Ye et al.
Frontiers in Genetics
Computational Drug Discovery Methods
article

Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson’s disease

Zheng Xu, Limei Zhang, Dailin Li, Zhiqiang Ye, Haoran Chen, Bo Yuan, Mo‐Li Wu, Qijun Yao
article en

Abstract

Our study provides insights into the shared molecular characteristics of PD and melanoma, identifying potential biomarkers for early diagnosis and prognosis and revealing new therapeutic targets. The discovery of retinoic acid as a promising therapeutic agent represents a significant step forward in drug development and treatment strategies for these diseases. This comprehensive analysis enhances our understanding of the intricate molecular mechanisms underlying the association between PD and melanoma, paving the way for further research and therapeutic advancements. The findings hold the promise of improved diagnosis, prognosis, and personalized treatment strategies for individuals affected by these debilitating diseases.

Frontiers in GeneticsVol. 16
Dalian Medical University (CN), Dalian University of Technology (CN), Second Affiliated Hospital of Dalian Medical University (CN), Dalian Municipal Central Hospital (CN), First Affiliated Hospital of Dalian Medical University (CN)
Good health and well-being
Openalex Percentile: Top 96%
Computational Drug Discovery Methods
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