Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson’s disease
Our study provides insights into the shared molecular characteristics of PD and melanoma, identifying potential biomarkers for early diagnosis and prognosis and revealing new therapeutic targets. The discovery of retinoic acid as a promising therapeutic agent represents a significant step forward in drug development and treatment strategies for these diseases. This comprehensive analysis enhances our understanding of the intricate molecular mechanisms underlying the association between PD and melanoma, paving the way for further research and therapeutic advancements. The findings hold the promise of improved diagnosis, prognosis, and personalized treatment strategies for individuals affected by these debilitating diseases.
Authors
- Zheng Xu (ORCID: https://orcid.org/0000-0003-0311-7004)
- Limei Zhang (ORCID: https://orcid.org/0000-0002-7422-5136)
- Dailin Li (ORCID: https://orcid.org/0009-0007-5113-4243)
- Zhiqiang Ye
- Haoran Chen (ORCID: https://orcid.org/0000-0002-3594-6897)
- Bo Yuan (ORCID: https://orcid.org/0000-0003-4544-7802)
- Mo‐Li Wu
- Qijun Yao
Institutions
- Dalian Medical University (CN)
- Dalian University of Technology (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- Dalian Municipal Central Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-02-24
- DOI
- https://doi.org/10.3389/fgene.2025.1526018
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00