Cepharanthine hydrochloride: a novel ferroptosis-inducing agent for prostate cancer treatment
This study has identified CH as a novel ferroptosis-inducing agent for the treatment of prostate cancer. The multiple mechanisms we found provides strong evidence for the eventual clinical application of the drug.
Authors
- Jingwen Guan (ORCID: https://orcid.org/0000-0003-1759-2172)
- Jianglin Fan (ORCID: https://orcid.org/0000-0002-1737-6130)
- Qiong Lin (ORCID: https://orcid.org/0000-0002-7964-6191)
- Ze-Xiu Huang
- Yao Wang (ORCID: https://orcid.org/0000-0002-5940-4988)
- Yifei Wang (ORCID: https://orcid.org/0000-0002-9918-2865)
- Yuqing Zhou (ORCID: https://orcid.org/0000-0002-6820-9121)
- Jing Jia (ORCID: https://orcid.org/0000-0001-6387-2437)
- Jing-Jie Zheng
Institutions
- Jinan University (CN)
- Wuyi University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-24
- DOI
- https://doi.org/10.3389/fphar.2025.1536375
- Citations
- 4
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 6.07