Evaluation of the clinical significance of BTG1 gene expression and pepsinogen in serum and cancerous tissue and gastric atrophy
The PGI/PGII ratio in serum emerged as a strong non-invasive biomarker for distinguishing cancer from healthy individuals. While BTG1 provides insights into gastric carcinogenesis, its clinical utility is limited due to the need for tissue samples. The serum-based PGI/PGII ratio shows greater promise as a non-invasive screening tool for GC.
Authors
- Mohammad Reza Abyaz
- Davood Alinezhad Dezfuli
- Maysam Mard‐Soltani (ORCID: https://orcid.org/0000-0002-9473-2901)
- Saeed Khalili (ORCID: https://orcid.org/0000-0003-0493-9595)
- Homa Hosseinpour
- Somayeh Pouria Mehr
- Yousef Paridar (ORCID: https://orcid.org/0000-0001-9727-4048)
- Neda Shakerian
Institutions
- Dezful University of Medical Sciences (IR)
- Shahid Rajaee Teacher Training University (IR)
Publication Details
- Journal
- Archives of Physiology and Biochemistry
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1080/13813455.2025.2458560
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00