Gold complex QB1561 suppresses drug-resistant cancer cells by inhibiting TrxR and mitochondrial respiratory function
QB1561 was effective for the treatment of MDR in drug-resistant cancer cells. Its further evaluation could be useful for the design and development of more gold-based anticancer drugs.
Authors
- Zhixin Shen (ORCID: https://orcid.org/0000-0001-7592-9082)
- Qingbin Cui (ORCID: https://orcid.org/0000-0003-2561-2962)
- Hailing Gao
- Wenwen Ding (ORCID: https://orcid.org/0009-0001-0935-0600)
Institutions
- Sun Yat-sen University (CN)
- Second Hospital of Shandong University (CN)
- Sun Yat-sen University Cancer Center (CN)
- University of Toledo (US)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-24
- DOI
- https://doi.org/10.3389/fphar.2025.1560880
- Citations
- 1
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 1.05