Comprehensive bioinformatics analysis of hub genes in ischemic heart failure and atrial fibrillation
The identified 10 hub genes can serve as potentially valuable biomarkers for IHF and AF. Enrichment analysis reveals that these potential biomarkers are significantly associated with ECM, nicotinate, and nicotinamide metabolism, providing a foundational target for the joint diagnosis and treatment of the two diseases.
Authors
- Meimei Zhou (ORCID: https://orcid.org/0000-0001-9838-1283)
- Lili Zhang (ORCID: https://orcid.org/0000-0002-3601-0150)
- Yushan Yang
- Jiejiao Zheng
- Youkang Xu
Institutions
- Fudan University (CN)
- Huadong Hospital (CN)
- Shanghai Second People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-02-24
- DOI
- https://doi.org/10.3389/fcvm.2025.1499065
- Citations
- 6
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 8.33