Rare neurological manifestation following hepatitis A infection: a report of 2 cases

Hepatitis A is the leading cause of acute viral hepatitis in developing countries. Extra-hepatic manifestation is very rare occurrence in Hepatitis A. We report 2 cases, one developing Acute Cerebellar Ataxia and another Opsoclonus Myoclonus Ataxia syndrome (OMAS). The former presented with Ataxia of acute onset one week after Hepatitis A infection. The patient did not have any neurological complication and responded to conservative management. The second patient was a 7-year-old girl presented with behavioral abnormality, jerky eye movements and ataxia with myoclonus following a Hepatitis A infection one week ago. Patient was treated with pulse dose methyl prednisolone followed by oral prednisolone and showed a prompt response. Neurological manifestation following Hepatitis A is a rare phenomenon.

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Publication Details

Journal
International Journal of Contemporary Pediatrics
Published
2025-02-24
DOI
https://doi.org/10.18203/2349-3291.ijcp20250418
Primary Topic
Hepatitis Viruses Studies and Epidemiology
Type
article
Field-Weighted Citation Impact
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article

Rare neurological manifestation following hepatitis A infection: a report of 2 cases

Soumya Sarkar, Sumit Pal, Aniruddha Nag
International Journal of Contemporary Pediatrics
Hepatitis Viruses Studies and Epidemiology
article

Rare neurological manifestation following hepatitis A infection: a report of 2 cases

Soumya Sarkar, Sumit Pal, Aniruddha Nag
article en

Abstract

Hepatitis A is the leading cause of acute viral hepatitis in developing countries. Extra-hepatic manifestation is very rare occurrence in Hepatitis A. We report 2 cases, one developing Acute Cerebellar Ataxia and another Opsoclonus Myoclonus Ataxia syndrome (OMAS). The former presented with Ataxia of acute onset one week after Hepatitis A infection. The patient did not have any neurological complication and responded to conservative management. The second patient was a 7-year-old girl presented with behavioral abnormality, jerky eye movements and ataxia with myoclonus following a Hepatitis A infection one week ago. Patient was treated with pulse dose methyl prednisolone followed by oral prednisolone and showed a prompt response. Neurological manifestation following Hepatitis A is a rare phenomenon.

International Journal of Contemporary PediatricsVol. 12(3)
Calcutta National Medical College and Hospital (IN)
Openalex Percentile: Top 95%
Hepatitis Viruses Studies and Epidemiology
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