Long-term outcomes of volume de-escalation for breast nodal irradiation

Improved patients' selection and a broader use of systemic therapy could make de-escalation a feasible option. However, this approach should be avoided in patients with extensive nodal involvement, specific molecular subtypes, or comorbidities that prevent the use of chemotherapy.

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Publication Details

Journal
Breast Cancer Research and Treatment
Published
2025-02-24
DOI
https://doi.org/10.1007/s10549-025-07652-3
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Long-term outcomes of volume de-escalation for breast nodal irradiation

G. S. Rossano, Luisa De Sanctis, Riccardo Ray Colciago, Valeria Faccenda et al.
Breast Cancer Research and Treatment
Breast Cancer Treatment Studies
article

Long-term outcomes of volume de-escalation for breast nodal irradiation

G. S. Rossano, Luisa De Sanctis, Riccardo Ray Colciago, Valeria Faccenda, S. Trivellato, Chiara Chissotti, Federica Ferrario, Stefano Arcangeli, Denis Panizza
article en

Abstract

Improved patients' selection and a broader use of systemic therapy could make de-escalation a feasible option. However, this approach should be avoided in patients with extensive nodal involvement, specific molecular subtypes, or comorbidities that prevent the use of chemotherapy.

Breast Cancer Research and TreatmentVol. 211(2)
Azienda Ospedaliera San Gerardo (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Milano-Bicocca (IT)
Università degli Studi di Milano-Bicocca
No poverty
Openalex Percentile: Top 96%
Breast Cancer Treatment Studies
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