Cordycepin Ameliorates Renal Interstitial Fibrosis by Inhibiting Drp1-Mediated Mitochondrial Fission
Cordycepin ameliorates renal fibrosis by targeting Drp1 to inhibit mitochondrial fission in injured renal tubular epithelial cells, reducing IL-6 secretion and inhibiting fibroblast activation.
Authors
- Yufei Lu (ORCID: https://orcid.org/0000-0002-7054-8421)
- Annan Chen
- Shi Jin (ORCID: https://orcid.org/0000-0002-3113-3186)
- Weize Chen
- Nana Song (ORCID: https://orcid.org/0000-0001-5703-2212)
- Wenye Geng (ORCID: https://orcid.org/0000-0002-3030-6014)
- Fang Yi (ORCID: https://orcid.org/0000-0003-4049-7245)
- Jian Zhang (ORCID: https://orcid.org/0000-0003-3373-9621)
- Jun Chen (ORCID: https://orcid.org/0000-0002-4327-4330)
- Zhixin Yan (ORCID: https://orcid.org/0000-0001-6448-4110)
- Yingxue Sun (ORCID: https://orcid.org/0009-0009-3373-5322)
- Xialian Xu (ORCID: https://orcid.org/0000-0003-0598-2149)
- Qiuyu Gu
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University (CN)
- Shanghai Changzheng Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/dddt.s498525
- Citations
- 7
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 5.64