Alteration of primary cilia and intraflagellar transport 20 (IFT20) expression in oral squamous cell carcinoma (OSCC) cell lines

This study reveals the differences in primary cilia expression among OSCC cells. Furthermore, the increased abundance and elongation of primary cilia in OSCC cells are accompanied by elevated expression of IFT20. Nonetheless, IFT20 did not affect MMP-9 mRNA expression in OSCC cells.

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Publication Details

Journal
PeerJ
Published
2025-02-24
DOI
https://doi.org/10.7717/peerj.18931
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Alteration of primary cilia and intraflagellar transport 20 (IFT20) expression in oral squamous cell carcinoma (OSCC) cell lines

Jonathan Wee Kent Liew, Nazia Abdul Majid, Siti Amalina Inche Zainal Abidin, Gulam Sakinah-Syed
PeerJ
Genetic and Kidney Cyst Diseases
article

Alteration of primary cilia and intraflagellar transport 20 (IFT20) expression in oral squamous cell carcinoma (OSCC) cell lines

Jonathan Wee Kent Liew, Nazia Abdul Majid, Siti Amalina Inche Zainal Abidin, Gulam Sakinah-Syed
article en

Abstract

This study reveals the differences in primary cilia expression among OSCC cells. Furthermore, the increased abundance and elongation of primary cilia in OSCC cells are accompanied by elevated expression of IFT20. Nonetheless, IFT20 did not affect MMP-9 mRNA expression in OSCC cells.

PeerJVol. 13
University of Malaya (MY)
Ministry of Higher Education, Malaysia
Openalex Percentile: Top 96%
Genetic and Kidney Cyst Diseases
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