Biomarkers of Endothelial Activation in Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage: A Prospective Cohort Study
Levels of vWF, E-selectin, thrombomodulin, syndecan-1 and MMP-9 were not associated with the occurrence of DCI, although higher levels of vWF and syndecan-1 were associated with poor outcome at six months. Further research is needed to establish the role of these biomarkers in aSAH patients.
Authors
- W. Peter Vandertop (ORCID: https://orcid.org/0000-0001-5417-0265)
- Bert A. Coert (ORCID: https://orcid.org/0000-0003-3277-031X)
- Dagmar Verbaan
- Maud A. Tjerkstra (ORCID: https://orcid.org/0000-0001-9060-3435)
- Nicole P. Juffermans (ORCID: https://orcid.org/0000-0002-3039-6574)
- René Post (ORCID: https://orcid.org/0000-0001-7844-6262)
- Maartje F. Serlé (ORCID: https://orcid.org/0009-0002-8879-322X)
Institutions
- Erasmus MC (NL)
- Amsterdam Neuroscience (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1017/cjn.2025.32
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00