Intravascular speckle contrast optical spectroscopy for blood flow monitoring

Accurate blood flow monitoring is essential for diagnosing and managing various medical conditions. However, existing techniques face limitations in assessing small or deeply located vessels, prompting the need for innovative alternatives. In this study, we present an intravascular speckle contrast optical spectroscopy (IVSCOS) system, leveraging fiber-optic technology for real-time blood flow measurement in dynamic vascular environments. The system integrates speckle contrast principles with a compact fiber-optic platform, enabling cost-effective and minimally invasive assessments using commercially available optical fibers. Validation experiments on blood flow mimicking phantom demonstrated high concordance with Doppler ultrasound, suggesting the system’s accuracy and reliability. The IVSCOS system offers a promising solution for real-time, precise blood flow monitoring, facilitating practical uses in clinical diagnostics and interventional procedures.