Assessment of the biosafety profile of <i>Galium verum in vitro</i> on myoblasts and <i>in ovo</i> on chorioallantoic membrane
The ethanolic extract of <i>G. verum</i> manifests a stimulating effect on cardiomyocytes, enhancing cell viability, and maintaining a normal elongated shape, cell number, and confluence, without significant signs of apoptosis and with a weak irritative effect <i>in ovo</i>. In addition, the extract demonstrated a protective effect against hemorrhage, lysis, and coagulation of blood vessels induced by sodium dodecyl sulfate on the CAM.
Authors
- Alexandra-Denisa Semenescu (ORCID: https://orcid.org/0000-0001-7718-4168)
- Alina Hegheş
- Alina Anton (ORCID: https://orcid.org/0000-0002-3818-5261)
- Sorin Lucian Bolintineanu (ORCID: https://orcid.org/0000-0002-3484-4565)
- Andreea Mihaela Kiș (ORCID: https://orcid.org/0009-0004-4581-8487)
- Alex-Robert Jîjie (ORCID: https://orcid.org/0000-0002-3619-2484)
- Diana Maria Morariu-Briciu
- Andreea Rata
- Ingrid Hrubaru
Institutions
- Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
Publication Details
- Journal
- World Journal of Cardiology
- Published
- 2025-02-24
- DOI
- https://doi.org/10.4330/wjc.v17.i2.102310
- Primary Topic
- Phytochemical and Pharmacological Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00