Helicobacter pylori infection as a risk factor for changes in some hematological and biochemical parameters among Egyptian population

Background: Helicobacter pylori can be an etiology of chronic gastritis, peptic ulcer, and stomach cancer. The aim was to evaluate the relationship between H. pylori infection and alterations in some hematological and biochemical parameters among the Egyptian people. Method: Ninety individuals with confirmed H. pylori infection by the fecal antigen were selected and then followed after a month of treatment with Levofloxacin, amoxicillin, and a proton pump inhibitor; they underwent testing again for hematological and biochemical parameters after treatment of H.pylori. Results: both groups, group A (Before treatment) and Group B (After 1 month of therapy), showed a statistically significant relation between the presence of H. pylori and the CBC values; patients with pre-existing dyslipidemia exhibited a link between H. pylori infection and reduced levels of HDL-C as well as elevated LDL-C and triglycerides. Conclusion: H. pylori is associated with changes in some hematological and biochemical parameters.

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Publication Details

Journal
african journal of gastroenterology and hepatology
Published
2025-02-22
DOI
https://doi.org/10.21608/ajgh.2025.342145.1071
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
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article

Helicobacter pylori infection as a risk factor for changes in some hematological and biochemical parameters among Egyptian population

A. M. Abu-Rayyan and N. A. Al-Hadidi, Eman Badr, mohamed gamal abdrabu, Hossam Aboelkheir
african journal of gastroenterology and hepatology
Helicobacter pylori-related gastroenterology studies
article

Helicobacter pylori infection as a risk factor for changes in some hematological and biochemical parameters among Egyptian population

A. M. Abu-Rayyan and N. A. Al-Hadidi, Eman Badr, mohamed gamal abdrabu, Hossam Aboelkheir
article en

Abstract

Background: Helicobacter pylori can be an etiology of chronic gastritis, peptic ulcer, and stomach cancer. The aim was to evaluate the relationship between H. pylori infection and alterations in some hematological and biochemical parameters among the Egyptian people. Method: Ninety individuals with confirmed H. pylori infection by the fecal antigen were selected and then followed after a month of treatment with Levofloxacin, amoxicillin, and a proton pump inhibitor; they underwent testing again for hematological and biochemical parameters after treatment of H.pylori. Results: both groups, group A (Before treatment) and Group B (After 1 month of therapy), showed a statistically significant relation between the presence of H. pylori and the CBC values; patients with pre-existing dyslipidemia exhibited a link between H. pylori infection and reduced levels of HDL-C as well as elevated LDL-C and triglycerides. Conclusion: H. pylori is associated with changes in some hematological and biochemical parameters.

african journal of gastroenterology and hepatologyVol. 8(1)
Damanhour University (EG), Mahidol Oxford Tropical Medicine Research Unit (TH), Alexandria University (EG)
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Helicobacter pylori-related gastroenterology studies
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