Prevalence and antimicrobial resistance of Klebsiella pneumoniae isolated from catheter-associated urinary tract infections in Minia University Hospitals, Egypt

Introduction and aim of the work: k. pneumoniae is an important cause of hospital acquired infections as urinary tract infections (UTIs) especially catheter-associated urinary tract infections (CAUTI) that account for 70% of UTI. The aim of this study is to access prevalence of K. pneumoniae among catheter-associated UTIs in hospital setting with regards to antimicrobial susceptibility pattern. Subjects and Methods: 192 catheterized patients with symptoms of UTI were enrolled in the study; from whom urine specimens were collected. Urine culture was done on MacConkey agar, colonies more than 105 CFU/ml are further identified for isolation of k. pneumoniae species and antimicrobial susceptibility testing was performed using disk diffusion method. Results: k. pneumoniae was isolated from 30.7% of inpatients with CAUTI; 94.9% of K. pneumoniae isolates showed multidrug resistance. Absolute resistance was recorded against imipenem while amikacin showed the least resistance (42.4%). Conclusion: Increased rates of multidrug resistant K. pneumoniae isolated from CAUTI which is considered a major health problem facing patients in hospitals and better antibiotic polices should be followed including avoiding exaggerated use of antimicrobial agents.