Prognostic Value of G8 Geriatric Screening and Meet-URO Scores in Metastatic Renal Cell Carcinoma Patients Receiving First-Line Ipilimumab-Nivolumab Combination Immunotherapy
The G8 score is an independent prognostic factor for OS but not PFS in mRCC patients receiving first-line ipilimumab-nivolumab. The Meet-URO score shows consistent prognostic ability for PFS and OS across age groups. These findings suggest that while G8 may be useful for individual patient-level OS prediction, the Meet-URO score may be superior for guiding treatment decisions in clinical practice.
Authors
- Lucia Fratino (ORCID: https://orcid.org/0000-0002-5550-0868)
- Fabio Calabrò (ORCID: https://orcid.org/0000-0002-7863-3540)
- Matteo Santoni (ORCID: https://orcid.org/0000-0001-7340-6173)
- Alessio Signori (ORCID: https://orcid.org/0000-0001-6289-9144)
- Davide Bimbatti
- Marina Campione (ORCID: https://orcid.org/0000-0003-0582-5303)
- Mimma Rizzo (ORCID: https://orcid.org/0000-0001-7743-741X)
- Sara Elena Rebuzzi (ORCID: https://orcid.org/0000-0003-0546-6304)
- Sergio Bracarda (ORCID: https://orcid.org/0000-0002-0703-2959)
- Ugo De Giorgi (ORCID: https://orcid.org/0000-0001-7520-2908)
- Ria Nagpal (ORCID: https://orcid.org/0000-0002-1114-3483)
- Giuseppe Fornarini (ORCID: https://orcid.org/0000-0003-4754-6572)
- Umberto Basso (ORCID: https://orcid.org/0000-0002-5075-2177)
- Diana Giannarelli (ORCID: https://orcid.org/0000-0002-6085-1195)
- Giuseppe Luigi Banna
- Pasquale Rescigno
Institutions
- Università degli Studi di Enna Kore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ospedale San Paolo (IT)
- Portsmouth Hospitals NHS Trust (GB)
- Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IT)
- Istituto Oncologico Veneto (IT)
- Azienda Ospedaliera S.Maria (IT)
- Centro di Riferimento Oncologico (IT)
- Ospedale Policlinico San Martino (IT)
- Candiolo Cancer Institute (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Ospedale di Macerata
- University of Bari Aldo Moro (IT)
- University of Portsmouth (GB)
- University of Genoa (IT)
- Newcastle University (GB)
Publication Details
- Journal
- Technology in Cancer Research & Treatment
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1177/15330338251316626
- Citations
- 1
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52