Rap1 overexpression boosts triterpenoid saponin production in yeast by enhancing precursor supply and heterologous gene expression
These results highlight Rap1 overexpression as a robust strategy to increase triterpenoid production in yeast cell factories. Additionally, this approach provides a versatile framework for enhancing both precursor supply and heterologous gene expression.
Authors
- Thi Thuy Nguyen (ORCID: https://orcid.org/0000-0002-5584-1013)
- Jiyoung Byun (ORCID: https://orcid.org/0000-0003-1628-0206)
- Soo-Hoon Park
- Byung‐Kwan Cho (ORCID: https://orcid.org/0000-0003-4788-4184)
- Sun‐Chang Kim
Institutions
- Korea Advanced Institute of Science and Technology (KR)
- Intelligent Synthetic Biology Center (KR)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s12934-025-02667-3
- Citations
- 2
- Primary Topic
- Plant biochemistry and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.61