Clinical application of targeted nanopore sequencing in pathogen detection in patients with sepsis
This study underscores the versatility of TNPseq in identifying diverse pathogens in sepsis samples, ensuring its application as a diagnostic when pathogens elude conventional isolation or are difficult to culture. It particularly highlights the significant differences of A. baumannii and C. striatum in the two patient groups, pointing to potential research directions. TNPseq's potential in sepsis diagnosis is promising.
Authors
- Y. Eugene Chen (ORCID: https://orcid.org/0000-0003-2357-7825)
- Mingdi Chen
- Yu Qian (ORCID: https://orcid.org/0000-0001-9742-3330)
- Lei Bao (ORCID: https://orcid.org/0000-0002-8243-2872)
- Xin Liu (ORCID: https://orcid.org/0000-0002-7546-5860)
- Yi Li (ORCID: https://orcid.org/0000-0002-2092-4505)
- Jie Zhang
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s12879-025-10604-3
- Citations
- 3
- Primary Topic
- Biosensors and Analytical Detection
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- National Natural Science Foundation of China