Lung toxicity related to trimethoprim/sulfamethoxazole: pharmacovigilance data review
We highlight statistically significant disproportionality for several trimethoprim/sulfamethoxazole-related LT patterns, which constitutes a pharmacovigilance signal. Trimethoprim/sulfamethoxazole-related LT is rare, but may be critical and even life-threatening. Physicians should be aware of potential trimethoprim/sulfamethoxazole-related LT and should inform their patients, since early intervention could prevent severe outcome.
Authors
- Maxime Hentzien (ORCID: https://orcid.org/0000-0003-2729-9420)
- Delphine Lebrun
- Brahim Azzouz (ORCID: https://orcid.org/0000-0002-4395-2445)
- Anne‐Lise Ruellan (ORCID: https://orcid.org/0000-0003-4036-1882)
- Firouzé Bani‐Sadr (ORCID: https://orcid.org/0000-0001-8268-866X)
- F. Lebargy
- M. Bonnet
- F. Givry
Institutions
- Inserm (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- Infections Cardiovasculaires Virales et inflammation en pathologie humaine
- Université de Reims Champagne-Ardenne (FR)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1093/jac/dkaf050
- Citations
- 5
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77