Metagenomic next-generation sequencing for etiological diagnosis of an unexpected rabies case with unclear exposure history
The identification of unique RABV sequence through mNGS in the patient's saliva sample suggested that mNGS could serve as a valuable screening tool for the etiological diagnosis of rabies, especially when timely laboratory testing was unavailable or when patients lacked non-specific prodromal symptom and clear exposure history.
Authors
- Jing Wu (ORCID: https://orcid.org/0000-0003-1931-4678)
- X.M Zhang
- Xinru Liu (ORCID: https://orcid.org/0000-0001-5427-0178)
- Jiangrong Chen
- Wenyan Zhang (ORCID: https://orcid.org/0000-0001-9765-784X)
- Yun Yang (ORCID: https://orcid.org/0000-0002-2709-6423)
- Yuru Shi (ORCID: https://orcid.org/0009-0000-5166-0437)
- Lixue Liu (ORCID: https://orcid.org/0009-0006-8630-6220)
- Yingjie Qi (ORCID: https://orcid.org/0000-0002-9532-9233)
Institutions
- BGI Group (China) (CN)
- University of Science and Technology of China (CN)
- Hefei Infectious Disease Hospital (CN)
- BGI Genomics
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s12879-025-10687-y
- Citations
- 1
- Primary Topic
- Rabies epidemiology and control
- Type
- article
- Field-Weighted Citation Impact
- 1.04