Levofloxacin to Prevent Bacterial Infection in Patients With Acute Myeloid Leukemia Treated by Venetoclax and Azacitidine: A Toulouse-Bordeaux DATAML Registry Study
Levofloxacin as primary prophylaxis in patients with AML treated with VEN-AZA seems to decrease the rate of documented infections even if the incidence of FN was not significantly decreased. This prophylaxis shaped a different clinical and microbiological landscape without significant increase of antibiotic resistance.
Authors
- Nathan Mottal (ORCID: https://orcid.org/0000-0003-3154-0707)
- Jennifer Guiraud (ORCID: https://orcid.org/0000-0002-4288-3265)
- Éric Delabesse (ORCID: https://orcid.org/0000-0002-0928-0753)
- Christian Récher (ORCID: https://orcid.org/0000-0002-3332-4525)
- Martin Gauthier (ORCID: https://orcid.org/0000-0001-5338-2071)
- Anne‐Charlotte de Grande
- Harmony Leroy (ORCID: https://orcid.org/0000-0002-1050-2536)
- Diane Lara
- Pierre‐Yves Dumas (ORCID: https://orcid.org/0000-0003-0119-3548)
- Xavier Brousse (ORCID: https://orcid.org/0000-0001-6345-9685)
- Audrey Bidet
- Emilie Bérard (ORCID: https://orcid.org/0000-0003-2451-5271)
- Sarah Bertoli (ORCID: https://orcid.org/0000-0003-1084-2781)
- Thibaut Leguay (ORCID: https://orcid.org/0000-0002-3123-4948)
- Pauline Floch
- K. Delavigne
- Leila Ghenim
- Léopoldine Lapierre (ORCID: https://orcid.org/0000-0001-9940-1725)
- Arnaud Pigneux
- Audrey Sarry
- Suzanne Tavitian (ORCID: https://orcid.org/0000-0001-9656-676X)
- Nicolas Rasandisona
- Clémentine Béranger
- Anne Banos (ORCID: https://orcid.org/0009-0002-9161-5141)
Institutions
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Rode Kruis Ziekenhuis (NL)
- Institut universitaire du cancer de Toulouse Oncopole (FR)
- Centre Hospitalier de la Côte Basque (FR)
- Groupe Cahors (France) (FR)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1093/ofid/ofaf105
- Citations
- 1
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.05