Decreased METTL3 in atrial myocytes promotes atrial fibrillation
Our study established the pathophysiological role of METTL3 involved in the development of AF and provided a potential mechanism-based target for its treatment.
Authors
- Chuiyu Kong
- Qing Zhou (ORCID: https://orcid.org/0000-0001-7737-9643)
- Wenxue Liu (ORCID: https://orcid.org/0000-0002-6539-0797)
- Hanqing Luo (ORCID: https://orcid.org/0009-0002-7885-5845)
- Jie Yang (ORCID: https://orcid.org/0000-0002-6004-5150)
- Ronghuang Yu
- Xiyu Zhu (ORCID: https://orcid.org/0000-0003-1172-9326)
- Jingjie Wang
- Dongjin Wang (ORCID: https://orcid.org/0009-0000-3871-3100)
- Lu Tang (ORCID: https://orcid.org/0000-0002-5971-7116)
- Jian Shi (ORCID: https://orcid.org/0000-0002-2498-8274)
- Qian Zhou (ORCID: https://orcid.org/0000-0002-7384-8307)
- Jialei Fu (ORCID: https://orcid.org/0000-0002-6691-6834)
- Fen Chen (ORCID: https://orcid.org/0000-0002-0434-106X)
- Wen-Sen Xie
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- EP Europace
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1093/europace/euaf021
- Citations
- 4
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Nanjing Medical Science and Technique Development Foundation