Does Size Matter? A Retrospective Study Analysing the Size of PI-RADS 4 Lesions and Its Associated Prostate Cancer Positivity with Transperineal Prostate Biopsy

PI-RADS 4 size does matter and is a useful predictor of CSPCa. In our study, a cut-off of 8.5 mm was identified. The combination of PI-RADS 4 with PSA density provides a specificity higher than 80% for CSPCa detection.

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Journal
Research and Reports in Urology
Published
2025-02-01
DOI
https://doi.org/10.2147/rru.s499930
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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article

Does Size Matter? A Retrospective Study Analysing the Size of PI-RADS 4 Lesions and Its Associated Prostate Cancer Positivity with Transperineal Prostate Biopsy

Flavio Ordones, Lodewikus Petrus Vermeulen, Paulo Roberto Kawano, Peter Gilling et al.
Research and Reports in Urology
Prostate Cancer Diagnosis and Treatment
article

Does Size Matter? A Retrospective Study Analysing the Size of PI-RADS 4 Lesions and Its Associated Prostate Cancer Positivity with Transperineal Prostate Biopsy

Flavio Ordones, Lodewikus Petrus Vermeulen, Paulo Roberto Kawano, Peter Gilling, Sam Robertson, Mark R. Fraundorfer, David Scholtz, Luiz Gustavo Modelli De Andrade, Ali Hooshyari, K. Maoate
article en

Abstract

PI-RADS 4 size does matter and is a useful predictor of CSPCa. In our study, a cut-off of 8.5 mm was identified. The combination of PI-RADS 4 with PSA density provides a specificity higher than 80% for CSPCa detection.

Research and Reports in UrologyVol. Volume 17
University of Auckland (NZ), Auckland City Hospital (NZ), Auckland University of Technology (NZ), Tauranga Hospital (NZ), Universidade Estadual Paulista (Unesp) (BR)
Good health and well-being
Openalex Percentile: Top 95%
Prostate Cancer Diagnosis and Treatment
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Does Size Matter? A Retrospective Study Analysing the Size of PI-RADS 4 Lesions and Its Associated Prostate Cancer Positivity with Transperineal Prostate Biopsy — Flavio Ordones, Lodewikus Petrus Vermeulen, et al. · Research and Reports in Urology (2025) | TGRS Research Map | TGRS