Isolation and characterization of bovine coronavirus variants with mutations in the hemagglutinin-esterase gene in dairy calves in China

These findings suggest that BCoV HE deleted/inserted variants are prevalent in cattle and exhibit various biological characteristics. We should be alert to these HE-variants with insertions or deletions in the RBD, which may increase the possibility of interspecies transmission.

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Publication Details

Journal
BMC Veterinary Research
Published
2025-02-24
DOI
https://doi.org/10.1186/s12917-025-04538-w
Citations
6
Primary Topic
Animal Virus Infections Studies
Type
article
Field-Weighted Citation Impact
7.16

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article

Isolation and characterization of bovine coronavirus variants with mutations in the hemagglutinin-esterase gene in dairy calves in China

Qingyun Gu, Huihua Jiang, Long Zhao, Kangkang Guo et al.
6 citations
BMC Veterinary Research
Animal Virus Infections Studies
7.16
article

Isolation and characterization of bovine coronavirus variants with mutations in the hemagglutinin-esterase gene in dairy calves in China

Qingyun Gu, Huihua Jiang, Long Zhao, Kangkang Guo, Haihui Gao, Shengqing Li, Xiaodong Kang, Dong Wang, Liang Zhang, Wenhui Liu
article en
6 citations

Abstract

These findings suggest that BCoV HE deleted/inserted variants are prevalent in cattle and exhibit various biological characteristics. We should be alert to these HE-variants with insertions or deletions in the RBD, which may increase the possibility of interspecies transmission.

BMC Veterinary ResearchVol. 21(1)
Qinghai University (CN), Tibet University (CN), Ningxia Academy of Agriculture and Forestry Sciences (CN), Northwest A&F University (CN)
Key Research and Development Program of Ningxia, Science and Technology Plan Projects of Tibet Autonomous Region
Openalex Percentile: Top 3%
Animal Virus Infections Studies
7.16
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Isolation and characterization of bovine coronavirus variants with mutations in the hemagglutinin-esterase gene in dairy calves in China — Qingyun Gu, Huihua Jiang, et al. · BMC Veterinary Research (2025) | TGRS Research Map | TGRS