Preventive Effect of Controlled-Release Dexamethasone on Cochlear Ossification in Meningitis Model

In pneumococcal meningitis, fibrosis and ossification occur more intensively in the basal turn of the cochlea. Controlled-release dexamethasone implants are effective in preventing cochlear ossification and fibrosis. The prevention from the structural damage indicates the potential role of these dexamethasone implants in post-meningitic hearing loss and easing cochlear implant surgeries.

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Publication Details

Journal
Annals of Otology Rhinology & Laryngology
Published
2025-02-24
DOI
https://doi.org/10.1177/00034894251322616
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00

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article

Preventive Effect of Controlled-Release Dexamethasone on Cochlear Ossification in Meningitis Model

Fakih Cihat Eravcı, Metin Doğan, Fahriye Kılınç, Miyase Orhan et al.
Annals of Otology Rhinology & Laryngology
Bacterial Infections and Vaccines
article

Preventive Effect of Controlled-Release Dexamethasone on Cochlear Ossification in Meningitis Model

Fakih Cihat Eravcı, Metin Doğan, Fahriye Kılınç, Miyase Orhan, Hamdi Arbağ, Ömer Kaplan
article en

Abstract

In pneumococcal meningitis, fibrosis and ossification occur more intensively in the basal turn of the cochlea. Controlled-release dexamethasone implants are effective in preventing cochlear ossification and fibrosis. The prevention from the structural damage indicates the potential role of these dexamethasone implants in post-meningitic hearing loss and easing cochlear implant surgeries.

Annals of Otology Rhinology & LaryngologyVol. 134(7)
Necmettin Erbakan University (TR)
Necmettin Erbakan Üniversitesi
Good health and well-being
Openalex Percentile: Top 96%
Bacterial Infections and Vaccines
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