Numerical study of interstitial fluid flow behavior in osteons under dynamic loading
Dynamic mechanical loading can significantly enhance the interstitial fluid flow in LCN by the changes of LCN pore volume. and dynamic loading promoted fluid flow in shallow lacunae significantly higher than that in deep lacunae. The relationship between changes of LCN pore volume and interstitial fluid flow behavior has implications for drug delivery and bone tissue engineering research.
Authors
- Xin Cui (ORCID: https://orcid.org/0000-0002-6114-9031)
- Chunqiu Zhang (ORCID: https://orcid.org/0000-0002-7953-5790)
- Baochuan Xiong
- Tianyu Liu (ORCID: https://orcid.org/0000-0003-0774-8663)
Institutions
- Tianjin University of Technology (CN)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s12891-025-08425-1
- Citations
- 3
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 5.16
Funders
- National Natural Science Foundation of China