Evaluation of Platelet-Rich Fibrin Membrane on Wound Healing Post-Gingivectomy Procedure

Evaluation of Platelet-Rich Fibrin Membrane on Wound Healing Post-Gingivectomy Procedure - Background: Gingival enlargement can be managed by scalpel gingivectomy. However, healing occurs by secondary intention. So, to promote healing Platelet rich fibrin (PRF) can be used as it is a rich source of growth factors. The present case series aims to evaluate the effect of PRF membrane on gingival wound healing by secondary intention. Materials and Methods: A total of 05 subjects, requiring gingivectomy, were selected. After gingivectomy, Platelet rich fibrin membrane was prepared in centrifugal machine then applied over the surgical site. Healing response was evaluated on 5th, 7th and 30th post-operative day. Results: On, 5th post-operative day, pain was mild in all the cases which completely subsided on 7th day post-operatively. Healing response was observed on 5th day post-operatively, showing almost complete epithelization with only few erythematous sites at gingival margin. However, on 30thpost-operative day, all the sites were completely healed. Conclusion: It can be concluded that PRF may be safely used as a soft tissue dressing in open wound to achieve uneventful healing. However, future studies with larger sample size should be carried out to establish definitive result. Keywords: Gingival Enlargement, Gingivectomy, Platelet Rich Fibrin, Platelet Concentrates