The impact of genetic variations in FPGS, MTHFR, and ATIC on methotrexate response among pediatric patients with acute lymphoblastic leukemia
Our findings offer valuable insights into the intricate interplay between genetic polymorphisms, MTX exposure, toxicities, and clinical outcomes in patients with ALL and have the potential to inform precision medicine strategies.
Authors
- Dan Zhao (ORCID: https://orcid.org/0000-0002-1593-598X)
- Xiaoyan Kong (ORCID: https://orcid.org/0000-0001-5763-8564)
- Shu‐Mei Wang (ORCID: https://orcid.org/0000-0001-5960-3314)
- Miao Li (ORCID: https://orcid.org/0000-0002-4360-1960)
Institutions
- Capital Medical University (CN)
- Chinese People's Armed Police Force Medical College Affiliated Hospital (CN)
- Beijing Shijitan Hospital (CN)
Publication Details
- Journal
- Pharmacogenetics and Genomics
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1097/fpc.0000000000000563
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88