Proteome-wide Mendelian randomization identifies causal plasma proteins in prostate cancer development
Our consistent results highlighted the important roles of plasma SMAD2 and CREB3L4 in the risk of prostate cancer. Further investigations on these proteins may reveal their potential in the prevention and treatment of prostate cancer.
Authors
- Ke Jin (ORCID: https://orcid.org/0000-0001-5371-3440)
- Zitong Yang (ORCID: https://orcid.org/0000-0003-2886-0988)
- Sida Hao (ORCID: https://orcid.org/0009-0000-4496-4125)
- Xiangyi Zheng
- Jian Wu (ORCID: https://orcid.org/0000-0002-2793-4810)
- Hong Chen (ORCID: https://orcid.org/0000-0002-8146-0943)
- Cheng Zhang (ORCID: https://orcid.org/0000-0003-0607-7140)
- Jiafeng Ding (ORCID: https://orcid.org/0009-0004-7884-821X)
Institutions
- Lishui University (CN)
- Lishui Central Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s40246-025-00724-x
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 7.27
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province