Lineage-specific variation in frequency and hotspots of recombination in invasive Escherichia coli
Our results highlight the variation in the propensity to exchange DNA via homologous recombination within a distinct population at narrow geographic and temporal ranges. Understanding the sources of the genetic variation in invasive E. coli will help inform the implementation of effective strategies to reduce the burden of disease and AMR.
Authors
- Odion O. Ikhimiukor (ORCID: https://orcid.org/0000-0002-3738-4584)
- Kathryn R. Piper (ORCID: https://orcid.org/0000-0003-2711-2347)
- Adrienne A. Workman (ORCID: https://orcid.org/0009-0007-5088-0690)
- Cheryl P. Andam (ORCID: https://orcid.org/0000-0003-4428-0924)
- Isabella W. Martin (ORCID: https://orcid.org/0000-0001-7974-9767)
- Stephanie S. R. Souza (ORCID: https://orcid.org/0000-0002-4207-8231)
Institutions
- Dartmouth College (US)
- Albany State University (US)
- Dartmouth–Hitchcock Medical Center (US)
- University at Albany, State University of New York (US)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s12864-025-11367-6
- Citations
- 1
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 1.80
Funders
- National Institutes of Health