Efficacy and Safety of Sotrovimab Versus Oral Antiviral for Early Treatment in High-Risk Patients in Omicron Era: A Multicenter Retrospective Study
Sotrovimab and oral antivirals demonstrated similar efficacy in preventing mortality and hospitalization among high-risk patients. Patient-specific factors, particularly cardiovascular comorbidities and immunosuppression, significantly influenced outcomes and should guide treatment choices.
Authors
- Fabio Giuliano Numis (ORCID: https://orcid.org/0000-0002-3638-4072)
- Martina Papillo
- Pierantonio Grimaldi (ORCID: https://orcid.org/0000-0001-9405-1834)
- Enrico Allegorico
- Guido Granata (ORCID: https://orcid.org/0000-0001-5796-0545)
- Mariantonietta Pisaturo (ORCID: https://orcid.org/0000-0001-5870-0956)
- Antonio Russo (ORCID: https://orcid.org/0000-0002-4224-5343)
- Nicola Coppola (ORCID: https://orcid.org/0009-0000-3202-5489)
- Chiara Cacace
- Augusta Troise
- Francesca Ambrisi
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- Ospedale Santa Maria (IT)
Publication Details
- Journal
- Pathogens
- Published
- 2025-02-22
- DOI
- https://doi.org/10.3390/pathogens14030216
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Regione Campania