Are New β-Lactam/β-Lactamase Inhibitor Combinations Promising Against Carbapenem-Resistant K. pneumoniae Isolates?
CZA demonstrates high efficacy against OXA-48-producing CRKP, making it a viable treatment option in settings where OXA-48 predominates. The limited activity of MEV in this study underscores the need for molecular surveillance of resistance mechanisms to guide empirical therapy.
Authors
- Abdurrahman Gülmez (ORCID: https://orcid.org/0000-0003-3953-5267)
- Mehmet Akif Durmuş (ORCID: https://orcid.org/0000-0002-3637-6451)
- Selda Kömeç (ORCID: https://orcid.org/0000-0002-6726-0048)
- Ayşe Nur Ceylan (ORCID: https://orcid.org/0000-0002-0049-6873)
- Kamuran Şanlı (ORCID: https://orcid.org/0000-0003-0814-5637)
- Beyza Öncel (ORCID: https://orcid.org/0000-0002-2857-8635)
Institutions
- University of Health Science (KH)
- State Hospital (GB)
- Sağlık Bilimleri Üniversitesi (TR)
Publication Details
- Journal
- Pathogens
- Published
- 2025-02-24
- DOI
- https://doi.org/10.3390/pathogens14030220
- Citations
- 5
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 2.96