m6A regulator-based molecular classification and hub genes associated with immune infiltration characteristics and clinical outcomes in diffuse gliomas
This work develops an immune- and clinical-relevant m6A subtyping and a scoring model, which enhances our understanding of the role of m6A modification in regulating immune infiltration microenvironment in gliomas and helps to identify patients who are more likely to benefit from immunotherapy.
Authors
- Siyu Chen (ORCID: https://orcid.org/0000-0002-6582-0945)
- Depei Li (ORCID: https://orcid.org/0000-0002-4317-1606)
- Wanming Hu (ORCID: https://orcid.org/0000-0002-3632-1258)
- Sai Ke
- Pingping Jiang (ORCID: https://orcid.org/0000-0002-6445-3370)
- Jie Lu (ORCID: https://orcid.org/0000-0003-1503-3801)
Institutions
- Sun Yat-sen University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1186/s12920-025-02104-9
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province